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guides.mclibrary.duke.edu/ebm

https://guides.mclibrary.duke.edu/ebm

PICO

What is the P.I.C.O. Model?

Defining a clinical question in terms of the specific patient problem aids the searcher in finding clinically relevant evidence in the literature. 

Essentially, PICO is a focused search strategy.

P-I-C-O Model for Clinical Questions

 P   Patient, Population, or Problem   How would I describe a group of patients similar to  mine? 
I  Intervention, Prognostic Factor, or  Exposure   Which main intervention, prognostic factor,
 or exposure am I considering?
C  Comparison or Intervention (if  appropriate)   What is the main alternative to compare 
 with the intervention?
O   Outcome you would like to   measure or  achieve  What can I hope to accomplish, measure, 
 improve, or affect?
T  Time Interval  What is the time interval to achieve desired outcomes?
   What type of question are you  asking?  Diagnosis, Etiology/Harm, Therapy, Prognosis,
  Prevention
   Type of study you want to find  What would be the best study design/methodology?

Table based on: Evidence Based Medicine: PICO. UIC Library.

What is Evidence-Based Medicine

"Evidence-based medicine is the conscientious, explicit, and judicious use of current best evidence
in making decisions about the care of individual patients. The practice of evidence-based medicine
means integrating individual clinical expertise with the best available external clinical evidence from
systematic research
.

- David Sackett et al in the 1996 article, "Evidence-Based Medicine:
What it is and what it isn't
" for BMJ. Full text here

Types of Studies

https://www.cebm.ox.ac.uk/resources/ebm-tools/study-designs

https://commons.wikimedia.org/wiki/File:Research_design_and_evidence.svg

Evidence-Based Practice series in American Journal of Nursing

Part 1:  Developing and Searching the Clinical Question

Part 2:  Critical Appraisal of the Evidence

Part 3:  Implementation

Part 4 : Disseminating the Evidence and Sustaining the Change

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